Welcome to the third episode of the Raw Talk Podcast! The theme for this month is “The Physician-Scientist”. To kick it off, we sit down with a man who’s got one foot in the clinic and the other in the lab: Dr. Norman Rosenblum, a pediatric and experimental nephrologist and researcher. In our chat with Dr. Rosenblum, we learn about what sparked his passion for nephrology, as well as the origins of his dual role as both physician and scientist.
The research focus of the Rosenblum lab lies in exploring the mechanisms that underlie normal and disrupted mammalian kidney development and the clinical outcomes in humans. Their research has greatly contributed to the discovery of the role of various proteins in controlling renal branching morphogenesis and nephron formation. Dr. Rosenblum’s enthusiasm about the field of pediatric nephrology comes across loud and clear in this episode. It comes as no surprise that he also leads a multi-center North American study aimed at identifying genetic defects that play a role in human renal malformation. Dr. Rosenblum touches on the major technological developments in his field and talks about the future directions for nephrology research. In keeping with this, Kat and Eryn take you on a “Flashback Friday” to discover the origins and impact of some of the most widely-used tools in laboratory research today: gene targeting and knockout mice.
In addition to his success in the field of nephrology, Dr. Rosenblum is also committed to training future clinician-scientists. Our hosts, Richie and Jabir, discuss Dr. Rosenblum’s own path to becoming a physician and a researcher, and his opinion on whether the clinician-scientist is an “endangered species”. In the “Ask a Student” segment, Kat and Eryn decide to sit down with future clinician-scientist, Swapna Mylabathula, to discuss what motivates her to pursue this route. She talks about her own experience in concussion research and the role she played in forming current policy around concussion injuries in children.
Dr. Rosenblum is a Canada Research Chair in developmental nephrology, staff nephrologist at the Hospital for Sick Children, senior scientist in developmental and stem cell biology at the Sick Kids Research Institute, and professor and Associate Dean of Physician Scientist Training at the University of Toronto. Visit the Rosenblum lab website to learn more about their groundbreaking research in renal development.